BFS Aseptic Filling Equipment for the

BFS Aseptic Filling Equipment for the Pharmaceutical Industry

Whether a bottle or an ampoule is to be filled, how it is filled, and what additional functions the container needs are usually based on the intended use. Rommelag’s bottelpack machines can manufacture canisters, bottles, tubes, ampoules, drop bottles, bellows containers, and portion packaging in a variety of forms and plastic blends, with filling volumes ranging from 0.04 to 10,000 ml, aseptically or conventionally – fully automatically and without human interference in all cases.

Pharmaceutical Packaging Solutions with BFS

  • Eye, ear, and nose drops
  • Homeopathics
  • Inhalation solutions
  • Infusions and injections
  • Rinsing solutions
  • Drinkable solutions
  • Creams, ointments, and gels
  • Wound care products
  • Vaginal applications
  • Rectal applications
  • Disinfectants
  • Diagnostic agents
  • Various biotechnological products
  • Oral applications
  • Ointments
  • Stability test kits
  • Sterile water
  • Temperature-sensitive products
  • for the biotech industry such as vaccines,
  • antibodies, and blood products
  • Wound gel
  • Wound irrigation products
  • And much more besides
Aseptic Filling in Heat-Sensitive Applications

Aseptic Filling in Heat-Sensitive Applications

The standard procedure is to fill products at room temperature. But in the pharmaceutical sector in particular, the products being filled can sometimes be highly temperature sensitive. Rommelag therefore developed coolBFS(R) for such instances. This involves special measures that maintain the product at a stipulated temperature before it is filled and that cool the newly molded plastic containers quickly. High processing speed is guaranteed and the product being filled is subject to maximum protection at all times. This is BFS at its best.

Single or Mutlilayer Pharmaceutical Packaging

Single or Mutlilayer Pharmaceutical Packaging

A single layer of polyethylene or polypropylene is usually more than adequate to contain the product safely and in accordance with its usage. But sometimes one layer simply isn’t enough, for example when the packaging solution has to perform other functions, too, in particular such as increasing the steam or gas barrier. In this and many similar cases, special bottelpack coex machines can be used to manufacture multilayer plastic packaging. Quite simply, this is packaging made of multiple layers that has precisely the right attributes to offer the product maximum protection. No matter what your product needs, Rommelag machines can manufacture the solution.

SEALING OR DOSING

SEALING OR DOSING

Eye drops, inhalation products, products for rectal or vaginal application, and ointments, creams, or gels – all BFS containers can be made ready to use and with the designated product and application in mind, and, if necessary, can be perfected with application-specific functional components.

UNIT-DOSE OR MULTIDOSE CONTAINERS

UNIT-DOSE OR MULTIDOSE CONTAINERS

No matter whether your product is designed for single or multiple use, our machines can mold the containers accordingly, accurately fill them, and add closing mechanisms in accordance with the requirements.

Luer Lock Connections

Luer Lock Connections

When syringes are used, the bottelpack ampoule design guarantees straightforward and reliable Luer fit or Luer lock connections. The liquid can be drawn up into the syringe simply, safely, and without the need for an additional needle. In the case of air-operated Luer connections, the pressure is equalized automatically. This is pretty neat and is just one of countless ways in which BFS technology offers veritable efficiency.

Aseptic Container Closure Technqiues

The right closure for you very much depends on the application and on whether the product is in a unit-dose or multidose container. What they all have in common is that each and every container is hermetically sealed, resulting in a closure that suits the function – and that’s clean and inexpensive, and functions reliably. The twist-off cap is a closure design which has proven its worth millions of times and which is used in a large number of production areas.

TWIST-OFF CAP

TWIST-OFF CAP

The twist-off cap is a closure design which has proven its worth millions of times and which is used in a large number of production areas.

KME

KME

The KME closure is complemented by a screw cap with a pin. Screwing the pin in creates an opening via which the product can be dripped or squeezed out.

KMT

KMT

The KMT closure consists of two parts and allows the user to accurately dispense drops of the product.

EUROHEAD CLOSURE

EUROHEAD CLOSURE

With the eurohead closure, the hermetically sealed container is combined with the eurohead cap. It was specifically designed to meet the requirements of infusion bottles (IV bottles).

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