What is BFS

How BFS Works – In 3 Seconds

B

Blow

Sterile polymer resin extruded into a mold to form the container.

F

Fill

The container is filled with the sterile product immediately.

S

Seal

The container is hermetically sealed – no exposure, no risk.

Benefits

Benefits of bottelpack Aseptic Filling Machines

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High Output, Low Unit Costs

Up to 33,300 containers/hour with low energy consumption and lean staffing requirements—driving competitive unit economics.

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Small Footprint

Our compact filling machines keep cleanroom requirements low, with only 7 m² of Class C cleanroom area at our 500 Series. Also, no separate washing, sterilizing, or capping trains are needed.

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Aseptic Assurance

Closed, automated processing without human intervention significantly reduces contamination risk versus open handling or multi‑step methods.

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Proven Reliability

Built with Swiss precision and German engineering since 1960, our bottelpack machines deliver high OEE year after year and are trusted by manufacturers worldwide.

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Quick Format Changes

Adapt filling volumes in ~15 minutes and complete format changes in <2 hours with the latest bottelpack generation, helping you stay agile in dynamic markets.

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Sustainable Production

Our latest generation achieves 80% less production waste, consumes 75% less energy, and saves 420,000 liters of water annually compared to previous models.

Machine Models

Aseptic Ampoule Filling Machines

Ideal for smaller filling volumes such as ophthalmics, inhalation solutions, and injectables. Up to 33,300 ampoules/hour with a filling volume of 0.1–50 ml.

Product Image bp_321M

bp 321M

Output: Up to 9.000 pcs/h
Filling volume: 0,1 – 50 ml
Ampoule length up to 208 mm
Ophthalmic, Inhalations, Injection, technical products
Product Image bp_360M

bp 360M

Output: Up to 18.000 pcs/h
Filling volume: 0,1 – 50 ml
Ampoule length up to 208 mm
Ophthalmic, Inhalations, Injection
Product Image bp_434

bp 434

Output: Up to 11.250 pcs/h
Filling volume: 0,1 – 30 ml
Closed parison and ampoule length up to 127 mm
Ophthalmic, Inhalations, Injection
Product Image bp_460-15

bp 460-15

Output: Up to 29.000 pcs/h
Filling volume: 0,1 – 30 ml
Closed parison and ampoule length up to 92 mm
Ophthalmic, Inhalations, Injection
Product Image bp_460-20

bp 460-20

Output: Up to 33.300 pcs/h
Filling volume: 0,1 – 20 ml
Closed parison and ampoule length up to 68 mm
Ophthalmic, Inhalations, Injection
Product Image bp_461

bp 461

Output: Up to 25.000 pcs/h
Filling volume: 3 – 60 ml
Closed parison and ampoule length up to 130 mm
Ophthalmic, Inhalations, Injection
Product Image bp_530

bp 530

Output: Up to 12.960 pcs/h
Filling volume: 0,1 – 20 ml
Closed parison and ampoule length up to 130 mm
Ophthalmic, Inhalations, Injection
Product Image bp_550

bp 550

Output: Up to 21.600 pcs/h
Filling volume: 0,1 – 20 ml
Closed parison and ampoule length up to 130 mm
Ophthalmic, Inhalations, Injection

Aseptic Bottle Filling Machines

For LVPs, infusion solutions, wound irrigation products, and other large-volume applications. Up to 10,000 bottles/hour; 50–2,000 ml.

Product Image bp_321

bp 321

Output: Up to 3.300 pcs/h
Filling volume: 50 – 2.000 ml
Bottles up to 303 mm
Infusions, Wound Irrigation Solutions, Injection
Product Image bp_324

bp 324

Output: Up to 4.000 pcs/h
Filling volume: 50 – 2.000 ml
Bottles up to 303 mm
Infusions, Wound Irrigation Solutions, Injection
Product Image bp_360

bp 360

Output: Up to 6.600 pcs/h
Filling volume: 50 – 2.000 ml
Bottles up to 303 mm
Infusions, Wound Irrigation Solutions, Injection
Product Image bp_364

bp 364

Output: Up to 10.000 pcs/h
Filling volume: 50 – 2.000 ml
Bottles up to 303 mm
Infusions, Wound Irrigation Solutions, Injection
qualifizierung-validierung

RPS

Qualification & Validation

Rommelag Pharma Service (RPS) accelerates and de‑risks qualification and validation for bottelpack systems—combining a proven Fast‑Track approach with modular packages and complete documentation support.

  • From URS through FAT/SAT and IQ/OQ/PQ, including documentation.
  • Fast‑Track: We prepare documentation before FAT and map relevant FAT/commissioning tests to Pre‑IQ / Pre‑OQ / IQ / OQ to reduce qualification duration by up to 40%.
  • Modular packages: Choose the right level of support; we’ll recommend scope during your consultation
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Compliance
Certified Production Processes

Our aseptic filling machines comply with the pharmaceutical industry's stringent requirements, including Annex 1 of the EU-GMP guidelines and those of various regulatory authorities, such as the EMA, FDA, Anvisa, and Abrasp.

Services

Lifecycle Services for bottelpack Systems

After Sales

Our comprehensive after-sales services ensure that your bottelpack machine delivers outstanding quality and operates economically day after day.

Factory Planning and Production Optimization

We have the expertise you need to plan, expand, reorganize, or optimize your BFS production.

Modernization and Upgrades

Given the extended lifecycle of our aseptic filling machines, we offer in-house modifications and upgrades to keep pace with new regulations and market demands.

Digitalization

Enable data insights, real-time monitoring, track your OEE, and more while ensuring the highest levels of data security.

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Find Your Ideal Aseptic Filling Machine

Let's translate our technology into your success and benefit from our expertise as the inventor and global market leader in blow-fill-seal technology. In your free, no-obligation consultation, we will guide you step by step to:

  • Identify the optimal machine configuration for your products
  • Estimate the delivery time of your bottelpack machine
  • Ensure seamless integration into your production environment
  • Forecast your ROI and highlight the clear economic value of BFS technology